In patients with arrhythmogenic right ventricular cardiomyopathy, ECG lead aVR morphology was associated with epicardial scar distribution and right ventricular dysfunction, though post-ablation ventricular arrhythmia recurrence did not significantly differ based on right ventricular outflow tract scar involvement.
Cohort (n=45)
No
Does ECG lead aVR morphology predict epicardial RVOT scar distribution and arrhythmic vulnerability in patients with ARVC?
In patients with ARVC, the R/Q ratio and morphology in ECG lead aVR provide a simple, noninvasive marker to predict epicardial RVOT scar distribution and right ventricular dysfunction, aiding in ablation procedural planning.
Absolute Event Rate: 42.9% vs 60%
p-value: p=0.249
Accurate, noninvasive markers reflecting epicardial scar distribution and guide ablation strategy in arrhythmogenic right ventricular cardiomyopathy remain limited.In this study, the R/Q ratio and morphology in electrocardiography (ECG) lead aVR were associated with right ventricular epicardial scar distribution and may help identify patients who require broader endocardial or epicardial ablation.These electrocardiographic indicators were also associated with right ventricular dysfunction and markers of arrhythmic vulnerability.Our findings suggest a simple ECG-based approach that may assist substrate characterization, procedural planning, and risk assessment.
Lee et al. (Wed,) conducted a cohort in Arrhythmogenic right ventricular cardiomyopathy (n=45). Epicardial right ventricular outflow tract scar involvement (≥50%) vs. No epicardial right ventricular outflow tract scar involvement (<50%) was evaluated on Post-ablation ventricular arrhythmia recurrence (p=0.249). In patients with arrhythmogenic right ventricular cardiomyopathy, ECG lead aVR morphology was associated with epicardial scar distribution and right ventricular dysfunction, though post-ablation ventricular arrhythmia recurrence did not significantly differ based on right ventricular outflow tract scar involvement.