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June 26, 2026Journal of Clinical Oncology0 citations

Evaluating a Hybrid AI-Powered Digital Health Guide for Genetic Testing in Hereditary Cancer

Evaluating a hybrid AI-powered digital health guide to improve informed decision making and streamline access to genetic testing for hereditary cancer.

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Authors

AKAnita KinneySTS. TundealaoEHEmily Heidt

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Overview

Randomized trial evaluates a digital health guide improving genetic testing uptake in cancer patients, suggesting enhanced decision-making support.

Key Points

  • The study aims to develop and assess the feasibility and efficacy of a hybrid AI-powered digital health guide to improve decision making on genetic testing.
  • Prototype developed through community-engaged formative research with focus groups and interviews.
  • Pilot trial randomized 28 participants to either the digital health guide or enhanced usual care.
  • Qualitative and quantitative analyses were employed to assess usability and efficacy.
  • Genetic testing uptake was significantly higher in the DHG arm (73.3%) compared to enhanced usual care (7.7%).
  • Participants in the DHG group reported lower decisional conflict (33.37 vs. 53.25) and decision regret (17.5 vs. 37.08) compared to EUC, with p < 0.05.
  • The Chatbot Usability Questionnaire average score indicated good acceptability (70.3).

Cite This Study

Kinney et al. (2026) studied this question.

synapsesocial.com/papers/6a3e170a030ad1a9b3090b4chttps://doi.org/10.1200/jco.2026.44.19_suppl.319
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