Key result
Review details endoplasmic reticulum-mitochondria interactions as potential therapeutic targets in ischemic stroke.
This review highlights the functional interaction between the endoplasmic reticulum and mitochondria in ischemic stroke to provide ideas for future research and treatment.
destabilization homeostasis, ER stress, oxidative stress, disordered mitochondrial quality control, and mitochondrial transfer. Additionally, this article highlights the functional interaction between the ER and mitochondria, as well as the mitochondrial-ER contacts (MERCs) that structurally connect mitochondria and the ER, aiming to provide ideas and references for the research and treatment of IS.
No takes yet. Share an insight, caveat, or question.
Zhang et al. (2025) conducted a review in Ischemic stroke. This review highlights the functional interaction between the endoplasmic reticulum and mitochondria, as well as mitochondrial-ER contacts, to provide perspectives for ischemic stroke research.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: