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June 25, 2026Dermatology ReportsOpen Access

Line-field confocal optical coherence tomography for biopsy-site selection and treatment monitoring in plaque morphea

Giuseppe P. A. Gemma C Dall'Ara Mirella Scattone Marco Virone Roberta De Carolis Luca Gargano Luca Fania Andrea Ascione Giovanni Pellacani Camilla Chello

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Key Points

This research aims to evaluate the use of line-field confocal optical coherence tomography for identifying active plaque morphea.
Utilized non-invasive imaging techniques to assess disease activity.
Focused on biopsy-site selection for accurate diagnostics and treatment.
Analyzed the correlation between imaging findings and clinical presentation.
Non-invasive imaging accurately identified active inflammatory areas in plaque morphea.
Improved treatment monitoring facilitated timely clinical management decisions.
Enhanced diagnostic accuracy led to better treatment outcomes observed in the study.

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Implication

Shows improved monitoring in plaque morphea, suggesting enhanced clinical management.

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Cite This Study

Gemma et al. (2026) studied this question.

synapsesocial.com/papers/6a3f68cdaea7db3c1953fc43 https://doi.org/10.4081/dr.2026.10923

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Possibilities of applying laser-induced fluorescence spectroscopy and Doppler flowmetry methods in the case of plaque morphea2025
2Towards effective targeted therapies in morpheaCase Report · 2026
3Clinical features and treatment of morphea patients: a retrospective analysis2025
4Multifocal linear morphea - a rare presentation with rapid progression and deformities in a young adult: a case report2024 · 1 citations
5Reverse Koebner Phenomenon in Linear Scalp Morphea Following Punch Biopsy: A Rare Therapeutic ResponseOriginal Research · 2026

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