Highlights the selective role of cardiopulmonary exercise testing in assessing exertional dyspnoea in interstitial lung disease, suggesting clinical implications.
Extract Exertional dyspnoea is nearly universal in interstitial lung disease (ILD) and remains a major driver of disability and impaired health-related quality of life [1, 2]. Yet one of the most familiar clinical conundrums in ILD is the dissociation between symptom burden and resting assessment. Despite comparable imaging and resting measures, a striking discrepancy exists in how individual patients tolerate the physiological demands of exertion and ordinary daily activity [3, 4]. This gap matters clinically: resting tests help to define disease severity and trajectory, but they do not adequately explain the physiology underlying exertional limitation.
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BALAKRISHNAN et al. (2026) studied this question.
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