Key result
Predictive equations using nonexercise variables can estimate peak oxygen uptake and heart rate in groups with Down syndrome, but large limits of agreement limit their use for individuals.
Why the study?
Can absolute peak oxygen uptake and peak heart rate be accurately estimated using nonexercise variables in persons with Down syndrome?
Observational
Can absolute peak oxygen uptake and peak heart rate be accurately estimated using nonexercise variables in persons with Down syndrome?
Predictive equations can estimate peak oxygen uptake and heart rate in groups with Down syndrome, but large limits of agreement limit their utility for individual patients.
Caution warranted for individual peak VO2 or HR estimates in Down syndrome; leaves open prospective validation of nonexercise equations.
Our data show that it is possible to estimate absolute peak oxygen uptake in persons with Down syndrome using nonexercise variables. Peak heart rate can also be accurately estimated in groups of people with and without Down syndrome. However, because of large limits of agreement, caution is advised if using these equations for individual estimations of peak oxygen uptake or peak heart rate in either population.
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Mendonça et al. (2021) conducted an observational in Down syndrome. Predictive equations using nonexercise variables was evaluated on Absolute peak oxygen uptake and peak heart rate. Predictive equations using nonexercise variables can estimate peak oxygen uptake and heart rate in groups with Down syndrome, but large limits of agreement limit their use for individuals.
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