Self-Switchable Polymerization: A Smart Approach to Sequence-Controlled Degradable Copolymers

In the quest for sustainable development, degradable polymers are attractive alternatives to traditional fossil-based plastics. As monocomponent degradable polymers often suffer from unsatisfactory performances, the utilization of corresponding copolymers with tailored block compositions is viable for improved properties. To this end, the emerging field of self-switchable polymerization offers a facile access to the on-demand synthesis of degradable copolymers with controlled sequences, in which the polymerizations were regulated by the monomers themselves. This Perspective outlines state-of-the-art self-switchable polymerization systems based on ring-opening (co)polymerization with various types of monomers. The scope of catalysts and monomer types are summarized. Comprehensive comparison between different types of monomers is offered along with an outlook on possible monomers in the future.