Key result
Intravenous fluid administration affects both macrocirculation and microcirculation, but hemodynamic coherence may be lost in disease states like sepsis, meaning macrocirculatory improvements do not always translate to microcirculatory recovery.
Highlights the importance of considering microcirculatory effects and the potential loss of hemodynamic coherence when administering intravenous fluids in critically ill patients.
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Bennett et al. (2018) conducted a review in Critical illness and shock. Intravenous fluid administration was evaluated. Intravenous fluid administration affects both macrocirculation and microcirculation, but hemodynamic coherence may be lost in disease states like sepsis, meaning macrocirculatory improvements do not always translate to microcirculatory recovery.
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