Rhabdomyolysis, renal failure and chronic neurologic deficits after prolonged immobilization from use of a 7-hydroxymitragynine product

Alyrene Dorey; Roy Gerona; Jacob Bell; Ross Ellison; Michael Moss

doi:10.1080/15563650.2026.2688230

June 26, 2026Clinical Toxicology

Rhabdomyolysis, renal failure and chronic neurologic deficits after prolonged immobilization from use of a 7-hydroxymitragynine product

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Key Points

Investigate the adverse effects of 7-hydroxymitragynine, specifically rhabdomyolysis and renal failure following immobilization.
Described a case involving prolonged immobilization due to 7-hydroxymitragynine use.
Assessed resulting complications, including renal failure and neurological deficits.
Patient experienced rhabdomyolysis with elevated creatine kinase levels.
Resulting renal failure required medical intervention, including dialysis.
Patient exhibited chronic neurologic deficits following recovery from initial complications.

Implication

Case report reveals chronic neurologic deficits after prolonged immobilization from 7-HMG product use, suggesting serious side effects.

Abstract

Dear EditorMitragynine, the major pharmacologically active compound contained in kratom, may be converted to 7-hydroxymitragynine (7-HMG) by in vivo metabolism or by chemical conversion in the labo...

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Cite This Study

Dorey et al. (2026) studied this question.

synapsesocial.com/papers/6a40ba8861bb0a67205c6684 https://doi.org/10.1080/15563650.2026.2688230

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Rhabdomyolysis, renal failure and chronic neurologic deficits after prolonged immobilization from use of a 7-hydroxymitragynine product

Key Points

Implication

Abstract

Discussion

Cite This Study

Rhabdomyolysis, renal failure and chronic neurologic deficits after prolonged immobilization from use of a 7-hydroxymitragynine product

Key Points

Implication

Abstract

Discussion

Cite This Study

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