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June 28, 2026Journal of Neurologic Physical Therapy

The Influence of Motor and Nonmotor Factors on Ambulatory Activity in People With Parkinson Disease

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Authors

CLCielita Lopez‐LennonJH Jennifer HaleARAnson Rosenfeldt

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Overview

Randomized trial examines motor and nonmotor impacts on daily steps in Parkinson disease, suggesting crucial nonmotor assessments.

Key Points

  • This study aims to explore how motor severity and nonmotor symptoms influence daily ambulatory activity in individuals with Parkinson disease.
  • Calculated mean daily steps over 7 days in 198 individuals with Parkinson disease.
  • Assessed motor and nonmotor symptoms using MDS-UPDRS Part I, III, and IV.
  • Used linear regressions to model associations between symptoms and activity while adjusting for age, race, and BMI.
  • Median daily step count was 5180 steps (IQR: 3521-7199).
  • Off-medication MDS-UPDRS III scores were linked to significantly fewer mean daily steps, while on-medication scores were not significant.
  • Self-reported lightheadedness was associated with approximately 2000 fewer mean daily steps.

Cite This Study

Lopez‐Lennon et al. (2026) studied this question.

synapsesocial.com/papers/6a40bb4561bb0a67205c6e5fhttps://doi.org/10.1097/npt.0000000000000573
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