Enantioselective electrophilic fluorination of β-keto esters with Selectfluor® catalyzed by DNA and a nonchiral ligand-Cu(II) complex is presented. The chirality transfer from DNA to the substrate appears to be caused by the intercalation or groove binding of the substrate-ligand-Cu(II) complex to DNA.
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Shibata et al. (2007) studied this question.