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The exceptional physicochemical and mechanical properties of mucus have inspired the development of dynamic mucus-based materials for a wide range of applications. Mucus's combination of noncovalent interactions and rich liquid phases confer a range of properties. This perspective explores the synergy between dynamic networks and functional liquids in mucus-inspired supramolecular adhesives. It delves into the biological principles underlying mucus's dynamic regulation and adhesive properties, the fundamentals of supramolecular adhesive design, and the transformative potential of these materials in biomedical applications. Finally, this perspective proposes potential directions for the molecular engineering of mucus-inspired supramolecular materials, emphasizing the need for interdisciplinary approaches to harness their full potential for biomedical and sustainable applications.
Hou et al. (Mon,) studied this question.
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