Key result
Biopsy-proved myocarditis shows 5-year survival similar to idiopathic dilated cardiomyopathy.
Why the study?
Most prior studies of myocarditis natural history preceded the Dallas criteria, leaving the prognostic value of standardized biopsy findings in patients presenting with dilated cardiomyopathy unclear.
Does a diagnosis of biopsy-proved myocarditis compared to idiopathic dilated cardiomyopathy affect long-term survival in patients presenting with dilated cardiomyopathy?
Cohort (n=85)
No
Does a diagnosis of biopsy-proved myocarditis compared to idiopathic dilated cardiomyopathy affect long-term survival in patients presenting with dilated cardiomyopathy?
Similar prognosis in myocarditis versus idiopathic dilated cardiomyopathy should not yet alter management; leaves open etiology-specific prospective trials.
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Grogan et al. (1995) conducted a cohort in Biopsy-proved myocarditis and idiopathic dilated cardiomyopathy (n=85). Biopsy-proved myocarditis vs. Idiopathic dilated cardiomyopathy was evaluated on 5-year survival rate. Biopsy-proved myocarditis was associated with a 5-year survival rate of 56%, which was not different from the 54% survival rate observed in patients with idiopathic dilated cardiomyopathy.
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