Key result
Long-term diuretics linked to depleted muscle K and Mg alongside increased Na and water.
Observational (n=537)
Investigations regarding plasma and skeletal muscle electrolytes were carried out in 537 patients on long-term diuretic treatment (greater than 1 year) for arterial hypertension (n = 240) and/or congestive heart failure (n = 297). In both groups there were significant decreases in both plasma and skeletal muscle K and Mg, while the muscle Na values as well as the total and extracellular water content of skeletal muscle were increased.
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Dyckner et al. (1987) conducted an observational in Arterial hypertension and/or congestive heart failure (n=537). Long-term diuretic therapy was evaluated on Plasma and skeletal muscle electrolytes (K, Mg, Na) and water content. Long-term diuretic therapy in hypertension or heart failure was associated with significant decreases in plasma and muscle K and Mg, and increased muscle Na and water content.
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