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July 1, 2026Journal of Experimental OrthopaedicsOpen Access

Younger age and prior graft failure are associated with increased risk of ACL reinjury: Graft survival and contralateral ACL outcomes at a median 10.6‐year follow‐up after primary hamstring autograft reconstruction

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Authors

DPDiego Alarcón PericoJRJorge RojasSGSergio González

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Overview

Retrospective cohort study evaluates graft survival and contralateral ACL injury risk after hamstring autograft reconstruction, highlighting age and prior graft failure as key factors.

Key Points

  • This study aims to evaluate graft survival and the risk of contralateral ACL injury after primary hamstring autograft reconstruction.
  • Retrospective cohort study of 415 patients who underwent primary single-bundle hamstring tendon ACL reconstruction from 2005 to 2014.
  • Median follow-up of 10.6 years with Kaplan-Meier analysis for graft survival and Cox proportional hazards models for risk factors.
  • Graft failure assessed by revision, confirmed rupture, or characteristic instability.
  • Ten-year graft survival probability was 86.6% (95% CI, 82.8%–89.5%).
  • Patients aged 21 years or younger had a higher hazard of graft failure (aHR, 2.62; 95% CI, 1.49–4.61; p < 0.001).
  • Prior graft failure was linked to contralateral ACL injury risk (aHR, 3.25; 95% CI, 1.00–10.53; p = 0.050).

Cite This Study

Perico et al. (2026) studied this question.

synapsesocial.com/papers/6a44ae8c5cd2549c8bc43bdahttps://doi.org/10.1002/jeo2.70828
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