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Abstract Although the 4+3 cycloaddition reaction has seen considerable attention over the past 10–15 years, only a few investigations have been dedicated to the development of a catalytic, asymmetric process. This short review covers some of the advances made in the area of absolute stereocontrol in this higher order cycloaddition and will hopefully serve as an inspiration towards the development of asymmetric, catalytic versions of the reaction.
Michael Harmata (Wed,) studied this question.
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