Key result
Intracoronary administration of isosorbide dinitrate successfully relieved a right coronary artery spasm that had caused life-threatening ventricular tachycardia in a young cannabis smoker.
Case Report (n=1)
Coronary artery spasm can present as life-threatening ventricular tachycardia in young cannabis smokers even in the absence of underlying atherosclerotic coronary artery disease.
Answers are grounded in this paper and cite their sources.
May prompt cannabis-use inquiry in young VT patients; leaves open causal confirmation via larger studies.
Vasospastic angina (VA), is characterized by symptoms of coronary angina caused by coronary vasospasm, usually in the absence of atherosclerotic changes. It typically presents with chest pain, which can be accompanied by transient electrocardiographic changes, if visualized during the attack. It can also rarely present with severe manifestations of acute myocardial angina, ventricular tachycardia (VT), ventricular fibrillation or cardiac arrest. We report the case of a 25-year-old male patient, with cannabis smoking habit, admitted for palpitations which had revealed a VT in the electrocardiogram (ECG), and for whom a coronary angiography was realised showing a coronary artery spasm (CAS) with no sign of atherosclerotic occlusion.
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Islah et al. (2022) conducted a case report in Coronary Artery Spasm and Ventricular Tachycardia (n=1). Intracoronary isosorbide dinitrate was evaluated on Relief of coronary artery spasm. Intracoronary administration of isosorbide dinitrate successfully relieved a right coronary artery spasm that had caused life-threatening ventricular tachycardia in a young cannabis smoker.
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