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The aim is to identify factors influencing mental health outcomes in patients with systemic sclerosis.

Factors influencing depression, anxiety, and quality of life in individuals with systemic sclerosis

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The aim is to identify factors influencing mental health outcomes in patients with systemic sclerosis.
Included 60 systemic sclerosis patients and a matched control group of 60 individuals.
Measured depression and anxiety using Hamilton scales and assessed quality of life with WHOQOL-BREF.
Performed logistic regression to analyze relationships between disease characteristics and mental health outcomes.
Depression prevalence was 66.7% and anxiety was 76.7% among systemic sclerosis patients.
Diffuse subtype of systemic sclerosis had 2.3 times higher odds of depression compared to limited subtype.
Quality of life was significantly poorer in diffuse systemic sclerosis patients across all domains (p < 0.05).

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Identifies mental health outcomes in systemic sclerosis patients, implying the need for focused assessments.

Mathur et al. (2026) studied this question.

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