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Shows enhanced live-cell imaging with bioorthogonal agents, suggesting improved visualization techniques.
, the first zero-distance tetrazinyl-coumarin, which can participate in fluorogenic IEDDA reactions with a range of dienophiles. The latter enables wash-free, real-time bioorthogonal imaging of labeled proteins and glycan targets on the surface of live cells, offering simple access to functional coumarins for advanced imaging applications.
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Patawanich et al. (2026) studied this question.
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