Key result
AKAP1 gene manipulation in hypoxic yak myocardial fibroblasts generates a non-targeted metabolomic dataset.
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Oxygen alters yak fibroblast metabolome; hypothesis-generating for cardiac hypoxia but leaves open human relevance.
The AKAP1 gene in yak myocardial fibroblasts was overexpressed and interfered with respectively, and then the cells were treated under normoxic (21%) and hypoxic (1%) conditions respectively. Finally, the cells were collected to determine their non-targeted metabolome data and related studies were conducted.
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王吉坤(Jikun Wang) (2026) studied this question. AKAP1 gene manipulation in yak myocardial fibroblasts under normoxic and hypoxic conditions generated a non-targeted metabolomic dataset for further analysis.
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