Examines the impact of corticosteroid therapy on cortical encephalitis in Crohn’s disease patients, suggesting MOGAD as a possible complication.
A 28-year-old man with Crohn’s disease receiving infliximab developed focal motor seizures with unilateral cortical hyperintensity on brain magnetic resonance imaging and serum myelin oligodendrocyte glycoprotein (MOG)-immunoglobulin G positivity, consistent with MOG antibody-associated disease (MOGAD) presenting as cortical encephalitis. His symptoms improved after corticosteroid therapy. MOGAD should be considered in patients receiving anti-tumor necrosis factor therapy who develop new-onset cortical manifestations.
No takes yet. Share an insight, caveat, or question.
Lee et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: