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This research investigates the cytotoxic effects of Trachyspermum ammi essential oil on various cancer cell lines.

July 2, 2026Open Access

Anticancer Activity of Oil of the Seeds of Trachyspermum Ammi

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Randomized trial evaluates cytotoxic effects of Trachyspermum ammi oil on cancer cells, suggesting therapeutic potential.

This research investigates the cytotoxic effects of Trachyspermum ammi essential oil on various cancer cell lines.
Volatile oil of T. ammi was tested on A549, HeLa, and AGS cancer cell lines using different concentrations (12.5-200 ug/ml) and analyzed with MTT assay.
Cisplatin was used as a standard control at 15 ug/ml for comparison.
Volatile oil showed IC50 values of 26.78 ug/ml for A549, 34.24 ug/ml for HeLa, and 171.02 ug/ml for AGS after 24 hours of incubation.
Effective toxicity was observed against all tested cancer cell lines.

2Ravinder Kashipeta *1Gomathi Periyasamy (2026) studied this question.

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