Key result
The definition of a biomarker should be provisionally renewed to describe any biological property whose in vitro measurement is useful for disease prevention, diagnosis, prognosis, or treatment.
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following definition of biomarker (or simply marker) might be provisionally used: “human or animal biological property whose in vitro measurement or identification is useful for the prevention, diagnosis, prognosis, treatment, and follow-up of human or animal diseases, and for their understanding”. As a final clarification, it should be kept in mind that in the field of clinical pharmacology (clinical trials) the concept of “biomarker” has a wider meaning than in clinical laboratory sciences: some biomarkers are in vitro measured or identified and others in vivo. In the field of clinical laboratory sciences, as reflected in the proposed definition, the concept of “biomarker” is always related to in vitro measurements or identifications.
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Xavier Fuentes‐Arderiu (2013) studied this question. The definition of a biomarker should be provisionally renewed to describe any biological property whose in vitro measurement is useful for disease prevention, diagnosis, prognosis, or treatment.
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