Case report reveals cutaneous T-cell lymphoma diagnosis in an adolescent, suggesting the need for awareness of rare cases.
Cutaneous T-cell lymphoma (CTCL) is a rare lymphoproliferative disorder and is infrequently encountered in adolescents.We report a 16-yearold female who presented with prolonged low-grade fever followed by progressive violaceous papulonodular lesions involving the face and extremities, accompanied by lymphadenopathy and generalized edema.Laboratory investigations revealed pancytopenia, hypoalbuminemia, and hepatosplenomegaly, with infectious and autoimmune causes excluded.Skin biopsy showed dense dermal infiltration by atypical lymphoid cells.Immunohistochemistry confirmed a T-cell phenotype with positivity for CD3, CD5, and CD30, and absence of B-cell markers, with a low proliferative index.Bone marrow examination revealed no malignant infiltration, supporting a primary cutaneous origin.The patient was managed conservatively and referred for specialized care.
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Biswas et al. (2026) studied this question.
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