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Case study demonstrates effective management of peristomal pyoderma gangrenosum in SLE, suggesting new treatment options.
BACKGROUND Peristomal pyoderma gangrenosum (PPG) is a rare complication of peristomal skin. It is difficult to manage, and there are no guidelines for treatment. This case study describes the management of a patient with PPG while taking corticosteroids and cyclosporine as chronic therapy for systemic lupus erythematosus (SLE). CASE Mrs. T had SLE and a colostomy and developed PPG that was unresponsive to previous treatment. She was successfully treated with a barrier film, a topical corticosteroid, and an alginate dressing. CONCLUSION The synergistic use of a barrier film, a topical corticosteroid, and an alginate proved to be effective for the management of PPG lesions in SLE.
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Denti et al. (2026) studied this question.
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