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July 4, 2026JCO Clinical Cancer Informatics

Patient-Reported Symptom Burden Among Thyroid Cancer Survivors: Retrospective Cohort Study

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Authors

JLJason B. LiuTYThomas Szabo YamashitaJRJohnny L. Rollins

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Overview

Retrospective cohort study examines symptom burden in thyroid cancer survivors, indicating variations needing attention.

Key Points

  • The aim is to examine patient-reported symptom burden among adult thyroid cancer survivors.
  • Conducted a retrospective cohort analysis from September 2019 to September 2022.
  • Administered the MDASI-Thy electronic questionnaire assessing symptom severity and interference before clinic visits.
  • Utilized multivariable generalized linear models to analyze associations with symptom scores and high alert values.
  • Among 1,557 thyroid cancer survivors, 864 (55.5%) responded.
  • Mean scores were 1.20 for core severity, 0.99 for thyroid-specific severity, and 1.07 for interference.
  • 72 survivors (8.3%) had high alert values for symptoms, with 54 (75%) having plans addressing these issues.

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/6a48a3cb89561a0c2d78d8b6https://doi.org/10.1200/cci-26-00041
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