Prospective trials and systematic reviews registrations are improving, but challenges remain about the quality of the evidence

Sean P. Riley; Daniel W. Flowers

doi:10.1080/10669817.2026.2696150

July 1, 2026Journal of Manual & Manipulative TherapyOpen Access

Prospective trials and systematic reviews registrations are improving, but challenges remain about the quality of the evidence

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Key Points

The research aims to assess the progress in systematic review registrations and the associated quality of evidence.
Analysis of historical trends in systematic review registrations and their assessment criteria.
Evaluation of risk of bias and publication bias in existing literature.
Recent increases in the quality of systematic reviews and registrations are noted.
Challenges in addressing publication bias and ensuring high-certainty evidence remain significant.

Implication

Prospective trials and systematic reviews registrations show improvements in evidence quality, indicating ongoing challenges remain.

Abstract

Historically, research synthesis through systematic reviews (SRs) involved assessing research quality, risk of bias, publication bias, and the certainty with which a consumer of the literature can ...

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Cite This Study

Riley et al. (2026) studied this question.

synapsesocial.com/papers/6a48a42489561a0c2d78daf6 https://doi.org/10.1080/10669817.2026.2696150

View Full Paper

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Prospective trials and systematic reviews registrations are improving, but challenges remain about the quality of the evidence

Key Points

Implication

Abstract

Discussion

Cite This Study

Prospective trials and systematic reviews registrations are improving, but challenges remain about the quality of the evidence

Key Points

Implication

Abstract

Discussion

Cite This Study

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