Key result
Higher skeletal muscle mass is linked to better cardiometabolic health and improved lipid profiles.
PURPOSE OF REVIEW: The purpose of this review was to present updated evidence on the role of skeletal muscle mass on cardiometabolic health. RECENT FINDINGS: Increased lean, and especially skeletal, muscle mass has been associated with better cardiometabolic health in various epidemiological studies, even in younger age groups. In addition, the link between skeletal muscle mass and adult lipid profile is of interest. A preliminary analysis using the data from the ATTICA prospective cohort study (2002-2022) supports this association. SUMMARY: Skeletal muscle mass has many metabolic functions (i.e., glucose, insulin and protein metabolism, mitochondrial function, arterial stiffness, inflammation, oxidative stress, brain function, hormone status). Given its associations with the lipid profile and overall cardiometabolic risk, skeletal muscle mass stands among the emerging risk factors for cardiovascular diseases. In addition to only using body mass index or fat distribution, more studies should evaluate lean mass and its prognostic and predictive ability regarding chronic diseases.
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Damigou et al. (2023) conducted a review in Cardiometabolic health and cardiovascular disease risk. Skeletal muscle mass was evaluated. Increased skeletal muscle mass is associated with better cardiometabolic health and improved adult lipid profiles, highlighting its emerging role as a protective factor against cardiovascular diseases.
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