Why the study?
With the expanding use of TAVI for aortic stenosis, evaluating real-life temporal trends in patient characteristics and clinical outcomes is important.
What are the temporal trends in patient characteristics, complications, and mortality among patients undergoing first-time TAVI?
Population
4,847 consecutive Danish patients undergoing first-time TAVI from 2010 to 2019
Comparison
Temporal trends over time (2010 to 2019)
Design
Nationwide register-based cohort study
Follow-up
90 days
Key result
In a nationwide Danish cohort, 30-day all-cause mortality after first-time TAVI significantly decreased from 6.7% in 2011 to 1.5% in 2019, alongside reductions in pacemaker implantation and heart failure.
Authors
Loading...
Short-term Danish TAVI mortality and complications declined over time; leaves open generalizability and causal drivers.
Cohort (n=4,847)
Yes
What are the temporal trends in patient characteristics, complications, and mortality among patients undergoing first-time TAVI?
Absolute Event Rate: 1.5% vs 6.7%
Real-world nationwide data from Denmark demonstrate significant reductions in 30- and 90-day mortality and complications (such as pacemaker implantation and heart failure) following TAVI from 2010 to 2019.
Lundahl et al. (2023) conducted a cohort in Aortic stenosis (n=4,847). Transcatheter aortic valve implantation (TAVI) vs. Earlier calendar years (2011) was evaluated on 30-day all-cause mortality. In a nationwide Danish cohort, 30-day all-cause mortality after first-time TAVI significantly decreased from 6.7% in 2011 to 1.5% in 2019, alongside reductions in pacemaker implantation and heart failure.