Real-time three-dimensional echocardiography demonstrated comparable results to conventional two-dimensional imaging for assessing global left ventricular ejection fraction (48.0% vs 47.3%, p=0.6).
Observational (n=70)
No
Does 3D echocardiography provide a feasible and quantitative assessment of regional wall motion abnormalities comparable to 2D echocardiography in patients with ischemic heart disease?
Three-dimensional echocardiography is a feasible, objective, and quantitative tool for detecting regional wall motion abnormalities that provides comparable results to conventional 2D echocardiography.
Tasa de eventos absoluta: 48% vs 47.3%
valor p: p=0.6
BACKGROUND: Three-dimensional echocardiography provides a volumetric measurement of global and regional left ventricular (LV) function. It avoids the subjectivity of 2D echocardiography in the assessment of regional wall motion abnormalities (RWMA). PURPOSE: Evaluate the feasibility and practicality of 3D echocardiography in the evaluation of ischemic patients with abnormal regional LV contractility. METHODS: The study included 40 patients with ischemic heart disease and RWMA as well as 30 control subjects. They underwent routine clinical examination and conventional 2D echocardiographic assessment. Segments were categorized as; normal, hypokinetic; akinetic or dyskinetic. Three-dimensional echocardiographic images were acquired and later on analyzed offline. Global LV function was semi-automatically calculated by the machine using volumetric measurements. Regional LV function was calculated manually for the 17 LV segments by detecting the end-diastolic (EDD) and end-systolic (ESD) points on the specific segment volume curve and the regional ejection fraction (EF) was calculated by the following formula (EDDx-ESDx) /EDDx, where x represents the specific segment. Regional EF was compared between patients and control subjects. RESULTS: The mean age was 55. 0 ± 8. 0 and 32. 6 ± 8. 5 years (P < 0. 001) in patients and control groups, respectively. No statistically significant difference in EF between 2D and 3D images (47. 3 ± 10. 5 vs 48. 0 ± 8. 0, p = 0. 6). There was a good correlation between the 2D-RWMA and 3D-regional EF, and this correlation was consistent in the whole 17 segments. CONCLUSION: Three-dimensional echocardiography is an easy, non-invasive and objective tool to detect regional wall motion abnormalities in ischemic patients. It shows comparable results with conventional 2D images with the advantage of quantitative assessment of regional myocardial function.
Youssef et al. (Fri,) conducted a observational in Coronary artery disease with regional wall motion abnormalities (n=70). Real-time three-dimensional echocardiography (RT3DE) vs. Conventional two-dimensional echocardiography (2DE) was evaluated on Global left ventricular ejection fraction (LVEF) (p=0.6). Real-time three-dimensional echocardiography demonstrated comparable results to conventional two-dimensional imaging for assessing global left ventricular ejection fraction (48.0% vs 47.3%, p=0.6).