July 5, 2026PLoS Biology0 citationsOpen Access
The cell cloud: Adopting systems biology concepts in the era of single-cell immunology
Key Points
- This research aims to introduce the 'cell cloud' model for analyzing single-cell data, addressing challenges in biological classification.
- Utilized high-throughput single-cell assays to gather extensive data.
- Developed the 'cell cloud' model based on systems biology principles.
- The model enhances understanding of biological variability in single-cell contexts.
- Data analysis supports addressing the limitations of discrete categorization in single-cell immunology.
Abstract
High-throughput single-cell assays reveal data that defies discrete categorization. The 'cell cloud' model, grounded in established systems biology principles, offers a framework to navigate biological plasticity alongside technical variability.