Key result
Frailty linked to ~35% higher 30-day mortality following perioperative CPR.
Why the study?
Despite growing focus on frailty for preoperative risk stratification and concern that CPR in frail patients may border on futility, the association between frailty and outcomes following perioperative CPR was unknown.
Does frailty (RAI ≥40) increase 30-day mortality and nonhome discharge in patients ≥50 years old receiving CPR after noncardiac surgery?
Cohort (n=3,149)
Yes
Does frailty (RAI ≥40) increase 30-day mortality and nonhome discharge in patients ≥50 years old receiving CPR after noncardiac surgery?
Odds Ratio: 1.35 (95% CI 1.11–1.65)
p-value: p=.003
Higher frailty burden (RAI ≥40) is associated with increased 30-day mortality and nonhome discharge following perioperative CPR in older adults undergoing noncardiac surgery.
Authors
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Frailty was associated with higher post-CPR mortality in surgical patients; leaves open whether frailty assessment should inform perioperative decisions.
Allen et al. (2023) conducted a cohort in Perioperative cardiac arrest (n=3,149). Frailty (Risk Analysis Index ≥ 40) vs. Risk Analysis Index < 40 was evaluated on Thirty-day mortality (AOR 1.35, 95% CI 1.11-1.65, p=.003). Frailty (Risk Analysis Index ≥40) was associated with increased 30-day mortality following perioperative CPR compared with an index <40 (adjusted OR 1.35; 95% CI 1.11-1.65; P=.003).
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