Exploring the potential of cognitive intra-individual variability in HIV care and research in adults with HIV: a concept analysis

Cognitive intraindividual variability (IIV) refers to the variability in one's ability to sustain consistent cognitive performance. This phenomenon is linked to the emergence of cognitive impairment and dementia. The aim of this concept analysis using Rodger's evolutionary approach was to clarify the unique characteristics of the concept of cognitive IIV in HIV care and research. PubMed, Embase, CINAHL, and PsycINFO were utilized which yielded 22 articles that were analyzed to inform the concept analysis. After considering antecedents, attributes, and consequences, many antecedents may also function as consequences, depending on how they influence or are influenced within the cause-and-effect process. This concept analysis highlights the potential of cognitive IIV as a sensitive indicator of cognitive health in people with HIV (PWH). A better understanding of the variation of cognitive performance in PWH will assist mental health professionals in developing more tailored interventions and achieving improved clinical outcomes.