SDH-proficient spindle-cell pediatric gist with peritoneal and umbilical metastatic deposits: A rare case report

Gastrointestinal stromal tumors (GISTs) are rare in children, comprising less than 2% of all GISTs and showing distinct clinical, radiologic, and molecular characteristics compared with adult cases. We present an 11-year-old girl with SDH-proficient spindle-cell pediatric GIST associated with peritoneal and umbilical metastatic deposits. Pediatric GISTs differ significantly from adult GISTs in biology and behavior. This case highlights these differences, emphasizing radiologic–pathologic correlation and the need for multidisciplinary management. Contribution: This case illustrates the rare case of Pediatric GIST, its imaging and pathological findings and its differentiating features from adult GIST.