Key result
Weight management fails to improve overall LE8 scores but benefits young adults with BMI <27.5.
Why the study?
Understanding factors that influence young adult cardiovascular health is essential to reduce morbidity and mortality.
Does a weight management intervention improve Life's Essential 8 metrics in young adults with overweight and obesity?
RCT (n=459)
Does a weight management intervention improve Life's Essential 8 metrics in young adults with overweight and obesity?
A weight management intervention in young adults with overweight and obesity did not significantly improve composite Life's Essential 8 scores over 18 months, highlighting the challenge of modifying overall cardiovascular health in this population.
May guide early CVH monitoring in young adults; leaves open whether weight management improves LE8 metrics.
BACKGROUND: It is essential to understand factors influencing young adult cardiovascular health (CVH) to reduce morbidity and mortality. OBJECTIVE: Evaluate longitudinal changes in CVH among young adults in a weight management intervention. METHODS: Life's Essential 8 (LE8) metrics were calculated for young adults with overweight and obesity enrolled in a randomized controlled trial (n = 459). Outcomes included LE8 total, LE8 behavior, LE8 health, and each LE8 metric. Linear mixed effects models evaluated associations between LE8 and intervention group and demographics and assessed longitudinal changes for 18 months. RESULTS: Although no composite LE8 scores changed over time, LE8 diet and blood glucose improved. Low socioeconomic status and non-White participants had lower scores for many LE8 metrics when controlling for time. A significant positive intervention effect on LE8 total was observed among those with baseline body mass index <27.5. CONCLUSION: Identifying factors associated with LE8 in young adulthood can support CVH, prevent future disease, and minimize health disparities.
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Cuccia et al. (2024) conducted an RCT in Overweight and obesity (n=459). Weight management intervention was evaluated on Life's Essential 8 (LE8) total, behavior, health, and each LE8 metric. A weight management intervention did not change composite Life's Essential 8 scores over 18 months overall, but showed a significant positive effect in young adults with baseline BMI <27.5.
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