March 12, 2014Journal of the American Chemical Society119 citationsOpen Access

Ligand-Controlled Asymmetric Arylation of Aliphatic α-Amino Anion Equivalents

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Abstract

A palladium-catalyzed asymmetric arylation of 9-aminofluorene-derived imines using a chiral dialkylbiaryl phosphine as the supporting ligand has been developed. This transformation allows for enantioselective access to a diverse range of α-branched benzylamines.

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Zhu et al. (Wed,) studied this question.

synapsesocial.com/papers/6a4c594efdb56635b009e7e5 https://doi.org/https://doi.org/10.1021/ja501560x

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