Acute Phosphate Nephropathy Following Oral Sodium Phosphate Bowel Preparation

Acute phosphate nephropathy (APN) is a rare but important cause of acute kidney injury (AKI), most commonly associated with the use of oral sodium phosphate bowel preparations administered prior to colonoscopy. In this report, we describe the case of a 60-year-old female patient who developed severe AKI necessitating temporary hemodialysis after bowel preparation with a phosphate-containing laxative. Quick identification, cessation of nephrotoxic agents, aggressive intravenous hydration, and supportive hemodialysis therapy facilitated gradual renal recovery. This case points out the importance of heightened awareness of APN, particularly in patients with multiple predisposing factors.