Key result
Higher diet-disease knowledge linked to ~12% lower odds of cardiovascular biomarker unawareness.
Why the study?
Diet-disease-related knowledge is theorized to foster healthier lifestyles, but the structural interconnectedness between nutritional knowledge and personal biomarker awareness is not well understood.
Does higher diet-disease-related knowledge improve cardiovascular biomarker awareness in healthy adults?
Cross-Sectional (n=406)
Does higher diet-disease-related knowledge improve cardiovascular biomarker awareness in healthy adults?
Odds Ratio: 0.878 (95% CI 0.824–0.936)
p-value: p=<0.001
Higher diet-disease-related knowledge is associated with better cardiovascular health literacy and Mediterranean diet adherence, highlighting the importance of cognitive frameworks in public health strategies.
Background/Objectives: Diet-disease-related knowledge (DDRK) is theorized to foster healthier lifestyles; however, the structural interconnectedness between nutritional knowledge and personal biomarker awareness is not well understood. This study aimed to identify independent predictors of DDRK and cardiovascular health (CVH) literacy among Lebanese adults using a psychometric framework. Methods: A cross-sectional convenience-sampled online survey was conducted among 406 Lebanese adults. Standard validated questionnaires were used, including the GNKQ-Section 4, GPAQ, and MEDAS. CVH literacy was computed as the total awareness of five main CV biomarkers: total cholesterol, LDL, HDL, triglycerides, and HbA1c. Data were analyzed through multivariable logistic regression and EBICglasso network analyses. Results: Overall, the prevalence of cardiovascular (CV) biomarker unawareness was 65.5% across participants. Fully adjusted regression models showed that a continuous DDRK score was a significant factor independently associated with lower odds of CV biomarker unawareness (aOR = 0.878, 95% CI [0.824–0.936], p < 0.001), followed by a higher MEDAS score (aOR = 0.842, p = 0.003) and aging (aOR = 0.961, p < 0.001). The network model was dense (sparsity = 0.133) and showed DDRK–CVH literacy as the strongest conditional edge (rpartial = 0.202). The conditional associations of BMI (r = 0.000) and physical activity (r = 0.036) with CVH literacy collapsed after conditioning on DDRK and MEDAS. Centrality indicators showed that DDRK had the highest closeness and strength (both = 1.000). Conclusions: DDRK shows strong conditional network associations with Mediterranean diet adherence and CVH literacy. These exploratory findings generate hypotheses for future longitudinal or interventional research.
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Dib et al. (2026) conducted a cross-sectional in Cardiovascular health literacy (n=406). Diet-disease-related knowledge (DDRK) was evaluated on Cardiovascular biomarker unawareness (aOR 0.878, 95% CI 0.824-0.936, p=<0.001). Higher diet-disease-related knowledge was independently associated with lower odds of cardiovascular biomarker unawareness (aOR 0.878).
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