Key result
LDL-C target achievement remains markedly suboptimal in people with HIV and established ASCVD, highlighting a gap between guideline recommendations and real-world practice.
There is a significant gap between guideline recommendations and real-world LDL-C target achievement in high-risk patients with HIV and ASCVD.
A substantial proportion of people with HIV and established atherosclerotic cardiovascular disease (ASCVD) meet criteria for extreme cardiovascular risk, yet low-density lipoprotein cholesterol (LDL-C) target achievement remains markedly suboptimal. Bridging the gap between updated guideline recommendations and real-world practice is essential to reduce recurrent ASCVD in this high-risk population.
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Giacomelli et al. (2026) conducted an editorial in HIV and established atherosclerotic cardiovascular disease (ASCVD). LDL-C target achievement remains markedly suboptimal in people with HIV and established ASCVD, highlighting a gap between guideline recommendations and real-world practice.
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