Key result
COPD shows ~9-fold greater respiratory variation in SVC systolic forward flow velocity than constrictive pericarditis.
Why the study?
Respiratory variation of >= 25% in mitral E velocity is used to diagnose constrictive pericarditis but can also occur in chronic obstructive pulmonary disease.
Observational (n=40)
Absolute Event Rate: 39.5% vs 4.2%
p-value: p=<0.0001
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May support Doppler differentiation of COPD from constrictive pericarditis; leaves open prospective validation before clinical adoption.
Boonyaratavej et al. (1998) conducted an observational in Chronic obstructive pulmonary disease and constrictive pericarditis (n=40). Chronic obstructive pulmonary disease vs. Constrictive pericarditis was evaluated on Respiratory variation in superior vena cava systolic forward flow velocity (p=<0.0001). COPD patients had significantly greater respiratory variation in superior vena cava systolic forward flow velocity than those with constrictive pericarditis (39.5 vs 4.2 cm/s, p<0.0001).
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