Key result
Echocardiographic assessment of mechanical dyssynchrony shows promise for improving patient selection for cardiac resynchronization therapy, though it has not yet replaced routine QRS criteria.
Why the study?
Do echocardiographic approaches to quantify mechanical dyssynchrony improve patient selection for CRT compared to electrocardiographic QRS complex width in patients with heart failure?
Do echocardiographic approaches to quantify mechanical dyssynchrony improve patient selection for CRT compared to electrocardiographic QRS complex width in patients with heart failure?
While echocardiographic assessment of mechanical dyssynchrony shows promise for future clinical applications, it has not yet replaced QRS width for CRT patient selection.
Echocardiographic dyssynchrony assessment does not replace QRS criteria for CRT; leaves open prospective validation trials.
Dyssynchrony is the abnormality in timing of regional ventricular mechanical activation in patients with heart failure. Dyssynchrony is one of the principal pathophysiologic features that improves with cardiac resynchronization therapy (CRT). Several echocardiographic approaches over the past several years have been described to quantify mechanical dyssynchrony in an attempt to improve patient selection over the electrocardiographic QRS complex width, which is a surrogate for dyssynchrony. Although no ideal method exists, this article focuses on the strengths and limitations of measures of longitudinal velocity using color tissue Doppler, radial strain using speckle tracking, and interventricular mechanical delay using routine pulsed Doppler. Recent results using these methods are exciting; however, they have not yet replaced routine clinical implant criteria for CRT. Echocardiographic assessment of dyssynchrony continues to evolve, with new information being added continually, and appears to have promise for future clinical applications.
No takes yet. Share an insight, caveat, or question.
葵 鈴木 (2000) conducted a review in Heart failure. Echocardiographic assessment of dyssynchrony vs. Electrocardiographic QRS complex width was evaluated. Echocardiographic assessment of mechanical dyssynchrony shows promise for improving patient selection for cardiac resynchronization therapy, though it has not yet replaced routine QRS criteria.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: