Key result
Percutaneous mechanical aspiration achieves high success in right-sided IE, with adverse events reflecting disease severity.
Why the study?
Right-sided infective endocarditis is increasingly prevalent, but cohorts evaluating percutaneous mechanical aspiration have been heterogeneous, predominantly comprising people who inject drugs and patients with cardiac device-related infections.
Observational
Yes
Multicenter analysis shows percutaneous mechanical aspiration effectively reduces vegetation in right-sided infective endocarditis, indicating a viable treatment for complex cases.
Right-sided infective endocarditis (RSIE) is increasingly prevalent, driven by injection drug use and utilization of cardiac implantable electronic devices (CIED).1,2 Percutaneous mechanical aspiration (PMA) has emerged as a catheter-based strategy for vegetation debulking in RSIE.3 In the Cardiac Lesion Extraction and Aspiration Registry for Infective Endocarditis (CLEAR-IE), PMA demonstrated high procedural success, with adverse events primarily reflecting underlying disease severity.3 However, the cohort was heterogeneous, with RSIE most commonly occurring in people who inject drugs (PWID) and patients with CIED-related infections.
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Heybati et al. (2026) conducted an observational in Right-Sided Infective Endocarditis. Percutaneous mechanical aspiration was evaluated. Percutaneous mechanical aspiration demonstrated high procedural success for right-sided infective endocarditis, with adverse events primarily reflecting underlying disease severity.
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