Key result
Heart transplantation in selected patients with severe cardiac amyloidosis resulted in a 1-year survival rate of 78% and a 2-year survival rate of 74%.
Why the study?
Heart transplantation in cardiac amyloidosis is possible when other organs are unaffected, but outcomes needed to be described and assessed at a referral center.
Does heart transplantation (alone or combined with liver/kidney) provide viable survival outcomes in selected patients with severe cardiac amyloidosis compared to nonamyloid patients?
Population
23 cardiac amyloidosis patients receiving heart transplants at a referral center
Comparison
Cardiac amyloidosis transplant recipients vs recipients with nonamyloid pathologies in France
Design
Single-center retrospective cohort study
Follow-up
2 y
Authors
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May support transplantation consideration in selected cardiac amyloidosis; hypothesis-generating given small observational cohort.
Cohort (n=23)
No
Does heart transplantation (alone or combined with liver/kidney) provide viable survival outcomes in selected patients with severe cardiac amyloidosis compared to nonamyloid patients?
Heart transplantation, either alone or combined with liver or kidney, offers survival outcomes in selected severe cardiac amyloidosis patients comparable to nonamyloid heart transplant recipients.
Guendouz et al. (2022) conducted a cohort in Cardiac amyloidosis (n=23). Heart transplantation vs. Recipients with nonamyloid pathologies was evaluated on 1-year survival rate. Heart transplantation in selected patients with severe cardiac amyloidosis resulted in a 1-year survival rate of 78% and a 2-year survival rate of 74%.