What is the clinical evidence from this study?

Study design: Cohort. Population: Measles-associated stridor (n=39). Intervention: Measles-associated stridor. Primary outcome: Hospital admission rate.

What does this research mean for the field?

Measles-associated stridor is a common complication in pediatric measles patients that presents with significantly greater severity, higher hospitalization and PICU admission rates, and a more prolonged clinical course compared to typical viral croup. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This study aims to characterize the clinical features and prevalence of stridor in patients with measles.

July 10, 2026PEDIATRICS

Measles-Associated Stridor

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Key result

Measles-associated stridor linked to severe clinical presentation and a ~90% hospital admission rate.

n=39

Why the study?

Measles-associated stridor is a historically recognized but poorly characterized complication of measles.

Population

39 patients aged 0 to 17 years with PCR-confirmed measles presenting with stridor

Design

Multicenter retrospective observational cohort study

Authors

IOI. OrenHadassah Medical Center LCLea Ohana Sarna CahanBeth Israel Deaconess Medical Center SGSegev Gil-adHebrew University of Jerusalem

Discussion

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Implication

Stridor in measles signals higher hospitalization and PICU risk than typical croup; leaves open whether specific protocols improve outcomes.

Key Points

This study aims to characterize the clinical features and prevalence of stridor in patients with measles.
Conducted a multicenter retrospective observational cohort study in 3 pediatric emergency departments from August 1 to October 31, 2025.
Included patients aged 0 to 17 years with PCR-confirmed measles presenting with stridor.
Assessed disease severity using the Westley Croup Score.
12% of measles patients presented with stridor, with a median age of 15 months and 85% unvaccinated.
89.7% required hospitalization and 17.9% were admitted to the pediatric intensive care unit (PICU).
The median length of hospital stay was 3 days, with significant respiratory compromise noted in 76.9% of patients.

Study Design

Type

Cohort (n=39)

Multicenter

Yes

Structured PICO

Population

39 pediatric patients aged 0 to 17 years with PCR-confirmed measles and stridor, evaluated retrospectively across 3 pediatric emergency departments.

Outcome

Clinical characteristics including incidence, clinical presentation, admission rate, treatment, and outcome (disease severity assessed using the Westley Croup Score)

Measles-associated stridor is a common (12%) and severe complication of measles in pediatric patients, characterized by high hospitalization and PICU admission rates compared to typical viral croup.

Limitations

Retrospective and observational nature preclude ruling out viral or bacterial coinfection in some cases.
Small sample size could have compromised the reliability of the analysis.
Retrospective and observational nature preclude ruling out viral or bacterial coinfection
Small sample size could have compromised the reliability of the analysis

Cite This Study

Oren et al. (2026) conducted a cohort in Measles-associated stridor (n=39). Measles-associated stridor was evaluated on Hospital admission rate. Measles-associated stridor occurred in 12% of pediatric measles cases and was associated with severe clinical presentation, leading to an 89.7% hospital admission rate and a 17.9% PICU admission rate.

synapsesocial.com/papers/6a508afd6eeac72a4379ff4b https://doi.org/10.1542/peds.2025-075788

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Implication

Stridor in measles signals higher hospitalization and PICU risk than typical croup; leaves open whether specific protocols improve outcomes.

Measles-Associated Stridor

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Limitations

Cite This Study

Measles-Associated Stridor

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider