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July 10, 2026Restorative Dentistry & EndodonticsOpen Access

Diagnostic accuracy of ChatGPT-5 in evaluating root canal treatment and periapical pathosis on periapical radiographs

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Authors

WAWaleed AlmutairiMAMujahid AlnasserHAHanan M. Alharbi

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Overview

Cross-sectional study assesses ChatGPT-5's diagnostic accuracy in evaluating dental radiographs, indicating limitations in sensitivity.

Key Points

  • This study aims to assess the diagnostic accuracy of ChatGPT-5 in interpreting periapical radiographs related to root canal treatments and identifying pathosis.
  • Cross-sectional study analyzing 271 anonymized periapical radiographs classified as straightforward or complex
  • Used standardized prompts for ChatGPT-5 and compared results with general dentists and endodontic specialists
  • Calculated sensitivity, specificity, and overall accuracy using the McNemar test.
  • ChatGPT-5 showed high specificity (up to 99.3%) for normal or adequately treated findings
  • Sensitivity for short obturations was 13.7%, and for voids, it ranged from 9.0% to 22.7%
  • Overall accuracy was significantly lower (54.0%-63.2%) than that of general dentists (76.0%-85.6%) with p < 0.001.

Cite This Study

Almutairi et al. (2026) studied this question.

synapsesocial.com/papers/6a508b536eeac72a437a0029https://doi.org/10.5395/rde.2026.51.e29
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