Tumor spheroids: opportunities for in vitro validation of anticancer drugs in imaging and targeted drug delivery

Amit Ranjan Maity; Thyageshwar Chandran; Surya K. Ghosh

doi:10.1080/20415990.2026.2699022

July 8, 2026Therapeutic Delivery

Tumor spheroids: opportunities for in vitro validation of anticancer drugs in imaging and targeted drug delivery

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Key Points

The study aims to evaluate the utility of multicellular tumor spheroids as a model for testing anticancer drugs.
Utilized 3D multicellular tumor spheroid models for drug testing
Evaluated imaging techniques for drug delivery
Assessed reproducibility and tunability of tumor spheroids
Demonstrated enhanced accuracy in drug response prediction using tumor spheroids
Illustrated significant differences in drug effectiveness compared to traditional models
Reported successful imaging of drug delivery mechanisms within spheroids

Implication

Explores anticancer drug responses in tumor spheroids, suggesting a valuable model for drug development.

Abstract

As cancer research continues to evolve, in-vitro three-dimensional (3D) multicellular tumor spheroid (MCTS) has emerged as one of the promising, reproducible, tunable models that precisely mimic...

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Cite This Study

Maity et al. (2026) studied this question.

synapsesocial.com/papers/6a508d096eeac72a437a0c18 https://doi.org/10.1080/20415990.2026.2699022

View Full Paper

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Tumor spheroids: opportunities for in vitro validation of anticancer drugs in imaging and targeted drug delivery

Key Points

Implication

Abstract

Discussion

Cite This Study

Tumor spheroids: opportunities for in vitro validation of anticancer drugs in imaging and targeted drug delivery

Key Points

Implication

Abstract

Discussion

Cite This Study

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