Key result
Ketogenic diets provide short-term metabolic gains but carry controversial cardiovascular risks and potential adverse events.
The treatment of obesity and cardiovascular diseases is one of the most difficult and important challenges nowadays. Weight loss is frequently offered as a therapy and is aimed at improving some of the components of the metabolic syndrome. Among various diets, ketogenic diets, which are very low in carbohydrates and usually high in fats and/or proteins, have gained in popularity. Results regarding the impact of such diets on cardiovascular risk factors are controversial, both in animals and humans, but some improvements notably in obesity and type 2 diabetes have been described. Unfortunately, these effects seem to be limited in time. Moreover, these diets are not totally safe and can be associated with some adverse events. Notably, in rodents, development of nonalcoholic fatty liver disease (NAFLD) and insulin resistance have been described. The aim of this review is to discuss the role of ketogenic diets on different cardiovascular risk factors in both animals and humans based on available evidence.
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Kosinski et al. (2017) conducted a review in Obesity and cardiovascular diseases. Ketogenic diets was evaluated on Cardiovascular risk factors. Ketogenic diets may offer temporary improvements in obesity and type 2 diabetes, but their impact on cardiovascular risk factors remains controversial and potentially associated with adverse events.
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