Case report describes rapid progression of sinonasal NUT carcinoma post-immunotherapy, suggesting early testing and surveillance.
This case report describes hyperacute destructive progression of sinonasal NUT carcinoma with new osseous metastasis shortly after pembrolizumab-based immunochemotherapy. The clinical course highlights the importance of early NUT testing, proactive systemic surveillance, cautious interpretation of immunotherapy response, and timely consideration of BET inhibition or clinical trial referral.
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Ye et al. (2026) studied this question.
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