Demonstrates greater symptom improvement in revision surgery patients on biologics with low CoSI scores, suggesting surgical completeness matters.
KEY POINTS: Revision surgery in patients on biologic therapy with lower preoperative CoSI scores (<70, reflecting previously incomplete surgery) resulted in significantly greater improvement in SNOT-22 after revision surgery compared to patients with previously adequate surgery. Incomplete prior surgery, as assessed by the CoSI, remains a likely correctable contributor to symptomatology even in patients receiving biologics.
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Thapar et al. (2026) studied this question.
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