Key result
Adverse reactions, medication aids, education, beliefs, and literacy predict medication burden in elderly CHD patients.
Why the study?
This study sought to examine the level of medication-related burden and explore its key determinants in elderly patients with coronary heart disease to inform strategies for optimizing medication management.
Cross-Sectional (n=231)
No
Elderly patients with coronary heart disease experience a moderate medication-related burden, which is independently associated with modifiable factors such as medication literacy, beliefs, and side effects.
Moderate MRB in elderly CHD patients flags modifiable factors for attention; leaves open whether targeted interventions improve adherence or outcomes.
Purpose: This cross-sectional study sought to examine the current level of medication-related burden (MRB) in elderly individuals with coronary heart disease (CHD) and to explore its key determinants. The findings are intended to inform strategies for optimizing medication management, mitigating MRB, and enhancing treatment adherence. Methods: A cross-sectional survey was conducted amongst 231 elderly patients diagnosed with CHD who were admitted to the cardiology ward of tertiary hospital in Hefei from January to March 2026. Data collection was performed using three assessment tools: the Chinese version of the Living with Medicines Questionnaire-3 (C-LMQ-3), the Chinese version of the Beliefs about Medicines Questionnaire (C-BMQ), and a reliable and valid Medication Literacy Scale. Statistical procedures included descriptive statistics, univariate tests, and multiple linear regression analyses. Results: Mean overall scores from the C-LMQ-3 and Visual Analogue Scale (VAS) both indicated moderate MRB among participants. Regression analysis indicated that medication adverse reactions, utilization of medication assistance devices, acquisition of medication-related health education, medication beliefs, and medication literacy were independent predictors of MRB (all P < 0.05). Conclusion: MRB levels among elderly CHD patients are moderate and are associated with various modifiable factors. Medical practitioners should implement holistic approaches to reduce MRB, with particular attention to enhancing medication literacy and addressing medication beliefs, alongside minimizing adverse drug events, encouraging the use of medication support tools, and reinforcing medication education.
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Zhou et al. (2026) conducted a cross-sectional in Coronary heart disease (n=231). Medication-related factors (adverse reactions, medication aids, education, beliefs, literacy) was evaluated on Medication-related burden (C-LMQ-3 score). Medication adverse reactions, use of medication aids, health education, medication beliefs, and medication literacy were identified as independent predictors of medication-related burden in elderly patients with coronary heart disease.
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